Hakan Çakmak

Name: Hakan CAKMAK

Position:

Assistant Professor

Division of Reproductive Endocrinology and Infertility Department of Obstetrics, Gynecology and Reproductive Sciences University of California, San Francisco

Address:

Box 0916

499 Illinois Street, 6th Floor

Division of Reproductive Endocrinology and Infertility Department of Obstetrics, Gynecology and Reproductive Sciences University of California, San Francisco

San Francisco, CA 94158

Office phone: (415) 353-7475 Office fax: (415) 353-7744 E-mail: hakan.cakmak@ucsf.edu

EDUCATION

1997 – 2003 Doctor of Medicine (M.D.)

Istanbul University, Cerrahpasa School of Medicine, Istanbul, Turkey

2006 – 2007 Preliminary Internship in Obstetrics and Gynecology

Yale – New Haven Hospital New Haven, CT

2007 – 2011 Residency in Obstetrics and Gynecology

Yale – New Haven Hospital New Haven, CT

2011 – 2014 Fellowship in Reproductive Endocrinology and Infertility

University of California, San Francisco San Francisco, CA

LICENSES, CERTIFICATION

2011 California Medical License, #A116910

2012 Board Certification in Obstetrics and Gynecology

2016 Board Certification in Reproductive Endocrinology and Infertility

PRINCIPAL POSITIONS HELD

2003 – 2006 Research Associate

Department of Obstetrics, Gynecology and Reproductive Sciences

Yale University School of Medicine New Haven, CT

2014 – current Assistant Professor

Division of Reproductive Endocrinology and Infertility Department of Obstetrics, Gynecology and Reproductive Sciences University of California, San Francisco

San Francisco, CA

HONORS AND AWARDS

1999 – 2003 The top ranked student award in 5 consecutive years

2003

Achieved the highest academic honors at graduation (Summa Cum Laude) from Istanbul University, Cerrahpasa School of Medicine. Class rank: 1 out of 256

2005

Wyeth President’s Presenter Award in 52nd Annual Meeting of the Society for

Gynecologic Investigation, Los Angeles, CA

2011 The Society of Laparoendoscopic Surgeons Resident Achievement Award

2011

The John J. Meehan – Clifford R. Miller Award for the graduating chief resident who most exemplifies the scholarly attributes of Obstetrics and Gynecology

2011 C. Lee Buxton Resident Research Award

2013

Pfizer President’s Presenter Award in 60th Annual Meeting of the Society for Gynecologic Investigation, Orlando, FL

2013

ASRM Corporate Member Council In-training Travel Award for the IFFS/ASRM 2013 meeting, Boston, MA.

2013

ASRM Fertility Preservation Special Interest Group’s Prize Paper Award at the

IFFS/ASRM 2013 meeting, Boston, MA.

2015

UCSF Outstanding Resident Teaching Award for exceptional achievements in resident

Education

2017

UCSF Outstanding Resident Teaching Award for exceptional achievements in resident Education

KEYWORDS/AREAS OF INTEREST

Infertility, assisted reproduction, oocyte biology, oocyte secreted factors, ovarian reserve, fertility preservation, prevention of gonadotoxic effects of chemotherapy, endometriosis, endometrial physiology, implantation, laparoscopic surgery.

PROFESSIONAL ACTIVITIES PROFESSIONAL ORGANIZATIONS Memberships

2011 – current American Society for Reproductive Medicine 2011 – 2015 San Francisco Medical Society

2012 – 2014 Society for the Study of Reproduction, Member

Service to Professional Organizations

2017 – current Society for Assisted Reproductive Technology (SART) Advertising Committee, Member.

INVITED PRESENTATIONS INTERNATIONAL

2006

International Symposium of Frontiers in Molecular and Cellular Biology in Reproduction

and Clinical Implications, Antalya, Turkey.

2016

Updates in Fertility Preservation in Cancer Patients, Istanbul University, 6th Obstetrics and Gynecology Days (December 9-12, 2016), Istanbul, Turkey.

NATIONAL

2006

Research in Progress, Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, CT.

2015

Prevention of chemotherapy-induced ovarian damage: Possible roles for hormonal and non-hormonal agents, Endocrine Grand Rounds, University of California, San Francisco, CA

2016

What did new approaches in fertility preservation teach us? Obstetrics, Gynecology and Reproductive Sciences Grand Rounds, University of California, San Francisco, CA

2017

What did new approaches in fertility preservation teach us about ovarian biology? Endocrine Grand Rounds, University of California, San Francisco, CA

COURSES ATTENDED

2013

Frontiers in Reproduction: Molecular and Cellular Concepts and Applications Marine Biological Laboratory

Woods Hole, MA

TEACHING AND MENTORING

2011 – current Instructor in the Laparoscopy Skills Lab for Students and Residents at University of

California, San Francisco

2014 – current Instructor in weekly Reproductive Endocrinology and Infertility fellow didactics at

University of California, San Francisco RESEARCH AND CREATIVE ACTIVITIES RESEARCH AWARDS AND GRANTS

PAST

T32HD007263-28 (PI) 2/2012-1/2013

NIH/NICHD

The effect of somatic cells and oocyte maturation on oocyte mRNA translation and protein secretion.

PEER REVIEWED PUBLICATIONS

1. Cakmak H, Schatz F, Huang JS, Buchwalder L, Rahman M, Arici A, and Lockwood CJ: Progestin Suppresses Thrombin and Interleukin-1β-Induced Interleukin-11 Production in Term Decidual Cells: Implications for Preterm Delivery. J Clin Endocrinol Metab. 2005 Sep;90(9):5279-5286.

2. Seli E, Kayisli UA, Cakmak H, Bukulmez O, Bildirici I, Guzeloglu-Kayisli O, and Arici A: Removal of Hydrosalpinges Increases Endometrial Leukemia Inhibitory Factor (LIF) Expression at the Time of Implantation Window. Hum Reprod. 2005 Nov;20(11): 3012-3017.

3. Berkkanoglu M, Zhang L, Ulukus M, Cakmak H, Kayisli UA, Kursun S, and Arici A: Inhibition of

Chemokines Prevents Intraperitoneal Adhesions in Mice. Hum Reprod. 2005 Nov;20(11): 3047-3052.

4. Seval Y, Cakmak H, Kayisli UA, and Arici A: Estrogen-Mediated Regulation of p38 Mitogen- activated Protein Kinase (MAPK) in Human Endometrium. J Clin Endocrinol Metab. 2006 Jun;91(6):2349-2357.

5. Matalliotakis IM, Cakmak H, Fragouli YG, Kourtis A, Arici A, and Huszar G: Increased IL-18 Levels in Seminal Plasma of Infertile Men with Genital Tract Infections. Am J Reprod Immunol. 2006 Jun;55(6):428-433.

6. Piotrowski PC, Kwintkiewicz J, Rzepczynska IJ, Seval Y, Cakmak H, Arici A, and Duleba AJ: Statins Inhibit Growth of Human Endometrial Stromal Cells Independently of Cholesterol Availability. Biol Reprod. 2006 Jul;75(1):107-111.

7. Seli E, Guzeloglu-Kayisli O, Cakmak H, Kayisli UA, Selam B, and Arici A: Estradiol Increases Apoptosis in Human Coronary Artery Endothelial Cells (HCAEC) by Up-regulating Fas and Fas Ligand Expression. J Clin Endocrinol Metab. 2006 Dec;91(12):4995-5001.

8. Matalliotakis IM, Cakmak H, Mahutte NG, Fragouli Y, Arici A, and Sakkas D: Women with Advanced Stage Endometriosis and Previous Surgery Respond Less Well to Gonadotropin Stimulation but have Similar IVF Implantation and Delivery Rates Compared to Women with Tubal- Factor Infertility. Fertil Steril. 2007 Dec;88(6):1568-1572.

9. Matalliotakis IM, Cakmak H, Arici A, Goumenou A, Fragouli Y, and Sakkas D: Epidemiological Factors Influencing IVF Outcome: Evidence from the Yale IVF Program. J Obstet Gynaecol. 2008 Feb;28(2):204-208.

10. Matalliotakis IM, Cakmak H, Dermitzaki D, Zervoudis S, Goumenou A, and Fragouli Y: Increased Rate of Endometriosis and Spontaneous Abortion in an in vitro Fertilization Program: No Correlation with Epidemiological Factors. Gynecol Endocrinol. 2008 Apr;24(4):194-198.

11. Matalliotakis IM, Cakmak H, Fragouli YG, Goumenou AG, Mahutte NG, and Arici A: Epidemiological Characteristics in Women with and without Endometriosis in the Yale Series. Arch Gynecol Obstet. 2008 May;277(5):389-393.

12. Matalliotakis IM, Cakmak H, Sakkas D, Mahutte N, Koumantakis G, and Arici A: Impact of Body Mass Index on IVF and ICSI Outcome: a Retrospective Study. Reprod Biomed Online. 2008 Jun;16(6):778-783.

13. Murk W, Atabekoglu CS, Cakmak H, Heper A, Ensari A, Kayisli UA, and Arici A: ERK Activity in the Human Endometrium: Possible Roles in the Pathogenesis of Endometriosis. J Clin Endocrinol Metab. 2008 Sep;93(9):3532-3540.

14. Kizilay G, Cakmak H, Yen CF, Atabekoglu C, Arici A, and Kayisli UA. Expression and Regulation of c-Jun N-terminal kinase (JNK) in Endometrial Cells in vivo and in vitro. Histochem Cell Biol. 2008 Oct;130(4):761-771.

15. Matalliotakis IM, Arici A, Cakmak H, Goumenou AG, Koumantakis G, and Mahutte NG: Familial

Aggregation of Endometriosis in the Yale Series. Arch Gynecol Obstet. 2008 Dec;278(6):507-511.

16. Matalliotakis IM, Cakmak H, Mahutte N, Goumenou AG, Koumantakis G, and Arici A: The Familial Risk of Breast Cancer in Women with Endometriosis from Yale series. Surg Oncol. 2008 Dec;17(4):289-293.

17. Matalliotakis IM, Cakmak H, Koumantakis EE, Margariti A, Neonaki M, and Goumenou AG:

Arguments for a Left Lateral Predisposition of Endometrioma. Fertil Steril. 2009 Apr;91(4):975-978.

18. Matalliotakis IM, Cakmak H, Goumenou A, Sifakis S, Ziogos E, and Arici A: ABO and Rh Blood

Groups Distribution in Patients with Endometriosis. Arch Gynecol Obstet. 2009 Dec;280(6):917-919

19. Cinar O, Seval Y, Uz YH, Cakmak H, Ulukus M, Kayisli UA, and Arici A: Differential Regulation

of Akt Phosphorylation in Endometriosis. Reprod Biomed Online. 2009 Dec;19(6):864-871.

20. Matalliotakis IM, Cakmak H, Krasonikolakis GD, Dermitzaki D, Fragouli Y, Vlastos G, and Arici A: Endometriosis Related to Family History of Malignancies in the Yale Series. Surg Oncol. 2010 Mar;19(1):33-37

21. Matalliotakis IM, Cakmak H, Sakkas D, Matalliotaki C, and Arici A: Assessment of oocyte and

embryo quality in women with endometriosis. J Endometriosis. 2010 Apr-Jun;2(2): 87-94.

22. Zuckerwise LC, Cakmak H and Sfakianaki AK: Uterine Dehiscence in Early Second Trimester.

Obstet Gynecol. 2011 Aug;118(2 Pt 2):497-500.

23. Matalliotakis IM, Cakmak H, Matalliotakis M, Kappou D and Arici A: High rate of allergies among

women with endometriosis. J Obstet Gynaecol. 2012 Apr;32(3):291-293.

24. Cakmak H, Basar M, Seval-Celik Y, Osteen KG, Duleba AJ, Taylor HS, Lockwood CJ and Arici A: Statins Inhibit Monocyte Chemotactic Protein-1 Expression in Endometriosis. Reprod Sci. 2012 June;19(6):572-579.

25. Cakmak H, Fujimoto VY, Zamah AM, Rosen MP, Tran ND, Cedars MI and Rinaudo PF: Metaphase II (MII) Oocytes Obtained at Different Time Points in the Same in Vitro Fertilization Cycle. J Assist Reprod Genet. 2012 Nov;29(11):1203-5.

26. Cakmak H, Katz A, Cedars MI and Rosen MP: Effective Method for Emergency Fertility

Preservation: Random Start Controlled Ovarian Stimulation. Fertil Steril. 2013 Dec;100(6):1673-80

27. Chen J, Torcia S, Xie F, Lin CJ, Cakmak H, Onodera C, Horner K, Song JS, Cedars MI, Ramalho- Santos M and Conti M: Somatic cells regulate maternal mRNA translation and developmental competence of mouse oocytes. Nat Cell Biol. 2013 Dec;15(12):1415-23.

28. Cakmak H, Tran ND, Zamah AM, Cedars MI, and Rosen MP: A Novel “Delayed Start” Protocol

with GnRH Antagonist Improves Outcomes in Poor Responders. Fertil Steril. 2014

May;101(5):1308-14.

29. Du H, Alawadhi F, Cakmak H, and Taylor HS: Bone Marrow-Derived Stem Cells (BMDSC) Transplantation Improves Fertility in a Murine Model of Asherman’s Syndrome. PLoS One. 2014 May 12;9(5):e96662.

30. Cakmak H, Franciosi F, Zamah AM, Cedars MI, and Conti M: Dynamic secretion during meiotic reentry integrates the function of the oocyte and cumulus cells. Proc Natl Acad Sci U S A. 2016 Mar 1;113(9):2424-9.

31. Quinn M, Cakmak H, Letourneau J, Cedars MI, and Rosen MP: Response to Ovarian Stimulation is

not Impacted by a Breast Cancer Diagnosis. Hum Reprod. 2017 Mar 1;32(3):568-574.

32. Herndon CN, Anaya Y, Noel M, Cakmak H, and Cedars MI. Outcomes from a University-based Low-cost in vitro Fertilization Program Providing Access to Care for a Low-resource Socioculturally Diverse Urban Community. Fertil Steril. 2017 Oct;108(4):642-649.

33. Cakmak H, Seval-Celik Y, Arlier S, Guzeloglu-Kayisli O, Schatz F, Arici A, Kayisli UA. p38 Mitogen-activated Protein Kinase is Involved in the Pathogenesis of Endometriosis by Modulating Inflammation, but not Cell Survival. Reprod Sci. 2017 Jan. [Epub ahead of print]

34. Letourneau J, Cakmak H, Quinn M, Sinha N, Cedars MI, and Rosen MP. Long-term Hormonal Contraceptive Use is Associated with a Reversible Suppression of Antral Follicle Count and a Break from Hormonal Contraception may Improve Oocyte Yield. J Assist Reprod Genet. 2017 Jul. [Epub ahead of print]

NON-PEER REVIEWED PUBLICATIONS AND OTHER CREATIVE ACTIVITIES

1. Cakmak H and Arici A: Müllerian Duct Anomalies. Turkiye Klinikleri J Pediatr Sci. 2006, 2(1):23-

29.

2. Ulukus M, Cakmak H, and Arici A: The Role of Endometrium in Endometriosis. J Soc Gynecol

Investig. 2006 Oct;13(7):467-476.

3. Kizilay H, Cakmak H, and Arici A: Endometriosis and Implantation. Trakya Univ Tip Fak Derg.

2007;24(2):90-97.

4. Cakmak H, Guzeloglu-Kayisli O, Kayisli UA, and Arici A: Immune – Endocrine Interactions in

Front Biosci (Elite Ed). 2009;1:429-443.

5. Cakmak H and Taylor HS: Progesterone – Hox Gene Interactions in Endometrium and Endometriosis: Molecular Mechanism of Treatment Resistance. Semin Reprod Med. 2010 Jan;28(1):69-74.

6. Cakmak H and Seli E: Use of Gonadotropin Releasing Hormone Agonists in Fertility Preservation. In: Agarwal and Seli, eds. Fertility preservation: Emerging Technologies and Clinical Applications. Springer/Humana Press, Berlin, Germany. 2011; 145-158.

7. Cakmak H and Taylor HS: The Implantation Failure: Molecular Mechanisms and Clinical

Treatment. Hum Reprod Update. 2011 Mar-Apr;17(2):242-253.

8. Cakmak H and Taylor HS: Assessment of Uterine Receptivity. In Nagy, Agarwal and Varghese, eds. Practical Manual of In Vitro Fertilization: Advanced Methods and Novel Devices. Springer Science and Business Media, New York. 2012; 559-566.

9. Kulp JL, Cakmak H and Taylor HS: Hox Genes and Endometriosis. In Evers, Healy and Giudice, eds. Endometriosis: Science and Practice. Blackwell Publishing Limited, Oxford, UK. 2012; 184- 189.

10. Cakmak H and Rosen MP: Selecting and Screening Recipients: Diminished Ovarian Reserve and Premature Ovarian Failure. In Sauer, eds. Principles of Oocyte and Embryo Donation, 2nd Edition. Springer Science and Business Media, New York. 2013; 47-63.

11. Cakmak H, Huddleston HG and Fujimoto VY: Reproductive and Assisted Reproductive Technology (ART) Outcomes in East Asian Women. In Sharara, eds. Ethnic Differences in Fertility and Assisted Reproduction. Springer Science and Business Media, New York. 2013; 95-104.

12. Cakmak H and Rosen MP: Ovarian Stimulation in Cancer Patients. Fertil Steril. 2013

May;99(6):1476-84.

13. Long RK and Cakmak H: Hypothalamic and Pituitary Hormones. In Katzung and Trevor, eds. Basic

and Clinical Pharmacology, 13th Edition. McGraw-Hill Education. 2015; 643-662.

14. Cakmak H and Rosen MP: Random-start ovarian stimulation in patients with cancer. Curr Opin

Obstet Gynecol. 2015 Jun;27(3):215-221.

15. Cakmak H and Rosen MP: Current Clinical Approaches to Protecting the Ovary: GnRH Analogues. In Anderson and Spears, eds. Cancer Treatment and the Ovary: Clinical and Laboratory Analysis of Ovarian Toxicity. Elsevier. 2015; 109-132.

ABSTRACTS

1. Erel C, Senturk L, Cakmak H, Ilvan S, Esen G, Uras C, and Ertungealp E: Does Mammographic Density Increase Indicate Any Significant Cytopathological Lesion among Woman on HRT? Presented at the 19th Annual Meeting of the European Society of Human Reproduction and Embryology, June 29 – July 2, 2003, Madrid, Spain.

2. Seval Y, Cakmak H, Kayisli UA, and Arici A: Inhibition of p38 MAP Kinase Decreases the Production of MCP-1 and IL-8 in Endometrial Stromal Cells. Presented at the 60th Annual Meeting of the American Society for Reproductive Medicine, October 16-20, 2004, Pennsylvania, PA.

3. Seval Y, Cakmak H, Kayisli UA, Demir R, and Arici A: Regulation of p38 MAP Kinase Phosphorylation by Estradiol in Endometrial Stromal Cells in vitro. Presented at the 60th Annual Meeting of the American Society for Reproductive Medicine, October 16-20, 2004, Pennsylvania, PA.

4. Cinar O, Seval Y, Cakmak H, Ulukus M, Can A, and Arici A: Differential Regulation of Akt Phosphorylation in Endometriosis by Estradiol. Presented at 52nd Annual Meeting of the Society for Gynecologic Investigation, March 23-26, 2005, Los Angeles, CA.

5. Seval Y, Cakmak H, Kwintkiewicz J, Duleba AJ, and Arici A: Statins Down-regulate Monocyte Chemotactic Protein-1 Expression in Endometrial Stromal Cells. Presented at 52nd Annual Meeting of the Society for Gynecologic Investigation, March 23-26, 2005, Los Angeles, CA.

6. Cakmak H, Seval Y, Schatz F, Lockwood CJ, and Arici A: Interleukin-11 Induces Proliferation of Eutopic and Ectopic Endometrial Stromal Cells: A Potential Autocrine Growth Factor in the Pathogenesis of Endometriosis. Presented at 52nd Annual Meeting of the Society for Gynecologic Investigation, March 23-26, 2005, Los Angeles, CA.

7. Cakmak H, Schatz F, Huang JS, Buchwalder L, Rahman M, Arici A, and Lockwood CJ: Progestin Suppresses Thrombin and Interleukin-1β-Induced Interleukin-11 Production in Term Decidual Cells: Implications for Preterm Delivery. Presented at 52nd Annual Meeting of the Society for Gynecologic Investigation, March 23-26, 2005, Los Angeles, CA.

8. Kayisli UA, Cakmak H, Seval Y, Donmez BO, and Arici A: In vivo Regulation of p38 MAPK Activation in Human Endometrium and Endometriosis. Presented at the 61st Annual Meeting of the American Society for Reproductive Medicine, October 15-19, 2005, Montreal, Canada.

9. Cakmak H, Donmez BO, Kayisli UA, and Arici A: Increased p38 Mitogen-activated Protein Kinase Activation in Endometriotic Endothelial Cells. Presented at the 61st Annual Meeting of the American Society for Reproductive Medicine, October 15-19, 2005, Montreal, Canada.

10. Tertemiz F, Asar M, Demir R, Cakmak H, Arici A, and Kayisli UA: Phospho-Akt and PTEN Expression in Normal and Preeclamptic Placentas: Possible Role for Phospho-Akt in Endothelial Dysfunction and Reduced Trophoblast Invasion in Preeclampsia. Presented at the 61st Annual Meeting of the American Society for Reproductive Medicine, October 15-19, 2005, Montreal, Canada.

11. Cakmak H, Ulukus M, and Arici A: Inhibition of Chemokines Reduces Post-Laparotomic Intraperitoneal Adhesions in Mice. Presented at the 61st Annual Meeting of the American Society for Reproductive Medicine, October 15-19, 2005, Montreal, Canada.

12. Lockwood CJ, Cakmak H, Huang JS, Funai EF, Norwitz ER, and Schatz F: Tumor Necrosis Factor Alpha Preferentially Enhances Matrix Metalloproteinase-9 Expression in First Trimester Human Decidual Cells: Implications for Preeclampsia. Presented at 53rd Annual Meeting of the Society for Gynecologic Investigation, March 22-25, 2006, Toronto, Canada.

13. Kayisli UA, Cakmak H, Atabekoglu CS, Kizilay G, Kim SH, and Arici A: Inhibition of P38, ERK and JNK MAPK Signaling Pathways Differentially Regulates Estrogenic Responsiveness and Cell Survival in Endometrial Cells. Presented at 53rd Annual Meeting of the Society for Gynecologic Investigation, March 22-25, 2006, Toronto, Canada.

14. Atabekoglu CS, Cakmak H, Heper A, Ensari A, Unlu C, Kayisli UA, and Arici A: In vivo and in vitro Regulation of ERK Activity by Sex Steroids in Glandular and Stromal Cells of the Human Endometrium. Presented at 53rd Annual Meeting of the Society for Gynecologic Investigation, March 22-25, 2006, Toronto, Canada.

15. Atabekoglu CS, Cakmak H, Heper A, Ensari A, Kayisli UA, and Arici A: Comparison of ERK Phosphorylation in Glandular and Stromal Cells Between Normal Endometrium and Endometriosis. Presented at 53rd Annual Meeting of the Society for Gynecologic Investigation, March 22-25, 2006, Toronto, Canada.

16. Cakmak H, Schatz F, Buchwalder L, Krikun G, Arici A, and Lockwood CJ: Progestin Suppresses Interleukin-1β-induced Cyclooxygenase-2 Expression and Prostaglandin Production in Term Decidual Cells: A Potential Mechanism for the Beneficial Effects of Progesterone Supplementation in the Prevention of Prematurity. Presented at 53rd Annual Meeting of the Society for Gynecologic Investigation, March 22-25, 2006, Toronto, Canada.

17. Cakmak H, Kayisli UA, Atabekoglu CS, Yen CF, Basar M, and Arici A: p38 MAPK is Involved in the Pathogenesis of Endometriosis by Modulating Inflammation and Cell survival. Presented at 53rd Annual Meeting of the Society for Gynecologic Investigation, March 22-25, 2006, Toronto, Canada.

18. Kim S, Yen CF, Atabekoglu CS, Cakmak H, Arici A, and Kayisli UA: Expression and Regulation of Integrin-Linked Kinase in Human Endometrium throughout the Menstrual Cycle and Early Pregnancy. Presented at the 62nd Annual Meeting of the American Society for Reproductive Medicine, October 21-25, 2006, New Orleans, LA.

19. Basar M, Cakmak H, Kizilay G, Kayisli UA, and Arici A: Increased Apoptosis in Macrophages in Endometriosis Implants: Implication for Immune-privileged Environment in Endometriosis. Presented at the 62nd Annual Meeting of the American Society for Reproductive Medicine, October 21-25, 2006, New Orleans, LA.

20. Kizilay G, Basar M, Cakmak H, Atabekoglu CS, Kayisli UA, and Arici A: C-Jun N-Terminal Kinase (JNK) Signaling Regulates Cell Proliferation and Apoptosis in Endometrial Cells. Presented at the 62nd Annual Meeting of the American Society for Reproductive Medicine, October 21-25, 2006, New Orleans, LA.

21. Cakmak H, Buchwalder L, Saccardi C, Arici A, Schatz F, and Lockwood CJ: Interleukin-1-induced Cyclooxygenase-2 and Prostaglandin Expression in Term Decidual Cells are Suppressed by Glucocorticoids and Progestin. Presented at 54th Annual Meeting of the Society for Gynecologic Investigation, March 14-17, 2007, Reno, NV.

22. Murk W, Uckac S, Uz YH, Cakmak H, Kayisli UA, and Arici A: ERK1/2 MAPK Activity is Involved in Human Endometrial Angiogenesis. Presented at 54th Annual Meeting of the Society for Gynecologic Investigation, March 14-17, 2007, Reno, NV.

23. Yen CF, Basar M, Buchwalder L, Cakmak H, Kayisli UA, Arici A, Schatz F, and Lockwood CJ: The Inflammatory Cytokines Induce Interleukin-11 Expression in Human Decidual Cells: Implications for Preeclampsia. Presented at 54th Annual Meeting of the Society for Gynecologic Investigation, March 14-17, 2007, Reno, NV.

24. Murk W, Uz YH, Cakmak H, Arici A, and Kayisli UA: ERK1/2 is Involved in Endometriotic Angiogenesis. Presented at 55th Annual Meeting of the Society for Gynecologic Investigation, March 26-29, 2008, San Diego, CA.

25. Buhimschi IA, Oliver E, Ali UA, Laky C, Cakmak H, Duzyj C, Zhao G, and Buhimschi CS: Novel Insights into the Mechanisms Responsible for the Up-Regulation of the Soluble Receptor for Advanced Glycation End-Products (Srage) in Severe Preeclampsia (Spe). Presented at 31st Annual Meeting of Society for Matenal-Fetal Medicine, February 7-12, 2011, San Francisco, CA.

26. Du H, Cakmak H, and Taylor HS: Localized Uterine Damage Recruits Bone Marrow-Derived Stem Cells throughout the Endometrium. Presented at 59th Annual Meeting of the Society for Gynecologic Investigation, March 21-24, 2012, San Diego, CA.

27. Cakmak H, Zamah AM, Katz A, Cedars MI, and Rosen PR: Effective Method for Emergency Fertility Preservation: Random-Start Controlled Ovarian Hyperstimulation. Presented at the 68th Annudal Meeting of the American Society for Reproductive Medicine, October 20-24, 2012, San Diego, CA.

28. Cakmak H, Chen J, Zamah AM, Cedars MI, and Conti M: Oocyte mRNA Translation and Protein Secretion is Associated with Maturation and is under the Control of Cumulus Cells. Presented at 60th Annual Meeting of the Society for Gynecologic Investigation, March 20-23, 2013, Orlando, FL.

29. Du H, Alawadhi F, Cakmak H, and Taylor HS: Bone Marrow-Derived Stem Cells Transplantation Improves Fertility in a Murine Model of Asherman’s Syndrome. Presented at 60th Annual Meeting of the Society for Gynecologic Investigation, March 20-23, 2013, Orlando, FL.

30. Cakmak H, Zamah AM, Ozawa T, Prados MP, Cedars MI, and Rosen MP: Anti-VEGF Antibody Treatment Protects Against Alkylating Chemotherapy Induced Gonadotoxicity in Mice. Presented at Conjoint Meeting of the International Federation of Fertility Societies and the American Society for Reproductive Medicine, October 12-17, 2013, Boston, MA.

31. Cakmak H, Tran ND, Zamah AM, Cedars MI, and Rosen MP: A Novel “Delayed Start” Protocol with GnRH Antagonist Improves Outcomes in Poor Responders. Presented at Conjoint Meeting of the International Federation of Fertility Societies and the American Society for Reproductive Medicine, October 12-17, 2013, Boston, MA.

32. Conti M, Franciosi F, Cakmak H, and Manandhar S: Molecular Pathways Involved in Oocyte Developmental Competence. Presented at 75th Annual Meeting of Pacific Division of the American Association for the Advancement of Science. June 17-20, 2014, Riverside, CA.

33. Cakmak H, Mok-Lin E, Katz A, Harris E, Chin-Yu C, Cedars MI, and Rosen MP: Random Start Controlled Ovarian Stimulation Results in High Oocyte Developmental Competence and Embryo Quality. Presented at the 70th Annual Meeting of the American Society for Reproductive Medicine, October 18-22, 2014, Honolulu, HI.

34. Cakmak H, Anaya Y, Huddleston HG, Cedars MI, and Rosen MP: Discontinuation of Long Term Use of Hormonal Contraceptives Leads to a Significant Increase in Antral Follicle Count and Oocyte Yield in Women Undergoing Elective Fertility Preservation or Donor Cycles. Presented at the 70th Annual Meeting of the American Society for Reproductive Medicine, October 18-22, 2014, Honolulu, HI.

35. Anaya Y, Cakmak H, and Fujimoto VY: Factors Predicting Oocyte Maturation in High Responders Undergoing Controlled Ovarian Hyperstimulation. Presented at the 70th Annual Meeting of the American Society for Reproductive Medicine, October 18-22, 2014, Honolulu, HI.

36. Zamah AM, Laeno AM, Cakmak H, and Xiong L: BMPR Signaling in the Mammalian Oocyte Improves Fertilization and Influences Early Embryo Development. Presented at the 70th Annual Meeting of the American Society for Reproductive Medicine, October 18-22, 2014, Honolulu, HI.

37. Cakmak H, Franciosi F, Cedars MI, and Conti M: Oocyte Secretion is Regulated by Somatic Cells during Oocyte Maturation and Mediates Cumulus Cell Function. Presented at the 71st Annual Meeting of the American Society for Reproductive Medicine, October 17-21, 2015, Baltimore, MD.

38. Anaya Y, Mata D, Ekpo G, Cakmak H, Cedars MI and Rosen MI: A Novel Treatment Strategy to Decrease OHSS Across All Stimulation Protocols. Presented at 64th Annual Meeting of Pacific Coast Reproductive Society (PCRS), March 9-13, 2016, Rancho Mirage, CA.

39. Anaya Y, Noel M, Cakmak H, Herndon CN, and Cedars MI: Outcomes from a University-Based, Low Cost IVF Program Providing Access of Care to a Socioculturally Diverse Urban Community. Presented at the 72nd Annual Meeting of the American Society for Reproductive Medicine, October 15-19, 2016, Salt Lake City, UT.

40. Quinn M, Cakmak H, Letourneau J, Cedars MI, and Rosen MP: Cancer Diagnosis is Associated with Equivalent Ovarian Reserve, Response to Ovarian Stimulation and Fertility Preservation Outcome when Compared to Elective Oocyte Cryopreservation. Presented at the 72nd Annual Meeting of the American Society for Reproductive Medicine, October 15-19, 2016, Salt Lake City, UT.

41. Quinn M, Cakmak H, Letourneau J, Cedars MI, and Rosen MP: Titration of Letrozole to Maintain Low Estradiol (E2) Levels During Fertility Preservation Cycles for Estrogen Receptor Positive (ER+) Breast Cancer Patients does not Impact Ovarian Response or Mature Oocyte Yield. Presented at the 72nd Annual Meeting of the American Society for Reproductive Medicine, October 15-19, 2016, Salt Lake City, UT.

42. Letourneau J, Cakmak H, Quinn M, Sinha N, Cedars MI, and Rosen MP: In Women Undergoing Elective Egg Cryopreservation with Less-Than-Expected Ovarian Reserve a 4 Month Break from Combined Hormonal Contraceptives is Associated with a 50% Increase in Oocyte Yield. Presented at the 72nd Annual Meeting of the American Society for Reproductive Medicine, October 15-19, 2016, Salt Lake City, UT.

43. Letourneau J, Sinha N, Harris E, Gomes E, Chin-Yu C, Cakmak H, Mok-Lin E, Cedars MI, and Rosen MP: Back-to-Back Random Start Ovarian Stimulation Prior to Chemotherapy Results in a Doubling of Oocyte Yield. Presented at the 73rd Annual Meeting of the American Society for Reproductive Medicine, October 28 – November 1, 2017, San Antonio, TX.